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While living in my college dorm during the winter of my junior year, I alarmed my friends, family, co-workers, and dorm mates by fasting on exclusively water for 14 days. I absolutely, positively, do not recommend fasting in this context, but at that time I was young, adventurous, motivated, and admittedly a bit reckless. As it turns out, it was one of the most extraordinary experiences of my life. In addition to so many other incredible and some unexpected benefits, my seasonal allergies that burdened a great deal of my childhood and adolescence up until that point in my life diminished by about 90%, which was absolutely amazing to me in addition to being a great relief.

Ten years later, after completing my doctorate degree, I became a staff doctor at the True North Health Center, a medically supervised, multi-disciplinary, water-only fasting facility in Northern California. During my four years there I had the opportunity to be involved in the care of nearly 1,000 fasting patients. I saw so many extraordinary healing experiences, including many that made my personal fasting experience look rather unremarkable by comparison!

I love speaking and teaching about ketosis, gluconeogenesis, autophagy, and the many other scientific and academic facets of the fasting experience. The bottom line about how fasting really works though is actually quite simple. Our bodies do have the capacity to heal themselves. When we overburden our body systems with extra calories, especially when those calories are from processed foods and foods that otherwise do not support our health, we undermine our body’s ability to heal itself to its fullest extent. This is extremely common in modern societies, so it’s no surprise that obesity, brain fog, low energy, type II diabetes, hypertension, heart disease, strokes, cancer, autoimmune diseases, etc. are so very common. But when we stop eating and rest, that healing capacity is given the greatest opportunity to express itself most fully, hence all the remarkable experiences that fasting patients have recovering from so many of the aforementioned health challenges and others. Not just occasionally, but from my experience, consistently, routinely, and predictably.

As incredible as fasting is, I’ll state the obvious in that it can only be utilized for relatively short periods of time, and is safest and most effective when under the care of a qualified healthcare provider.

How then do we allow the greatest amount of healing ability when we are eating?

In the 1930’s, Dr. Clive McCay and his research team at Cornell University discovered that when rats were placed on diets with lower calorie intakes than typical diets but still supplied needed nutrients, the rats lived about 33% longer than their normally fed counterparts. Amazing! Fewer calories, extended lifespan! Not only did they live longer, but they were healthier throughout their lifespan as well. Since that time, this has been repeated on many different species, ranging from simple protozoans to monkeys. Every time, every species, the same result. Fewer but adequate calories with nutrient needs met, leads to longer healthier lives.

There is some pretty good evidence that this strategy works well with humans, when we look at the healthiest, long-lived populations on the planet. They all consume fewer calories than is common, from nutrient dense foods. Within the scientific community this strategy is known as “caloric restriction.” I am not a big fan of that term, as “restriction” when it comes to food does not sound the least bit enjoyable. I prefer instead to use the term caloric optimization.

One amazing attribute of fruits and vegetables is that they are super high in nutrient density, while simultaneously being low in calorie density. This means we can eat a generous amount of them to feel full and satisfied, while providing ourselves with an abundance of needed nutrients, and optimizing our calorie intake all at the same time. How cool is that! No feelings of restriction! In fact, in order to obtain the majority of one’s calories from fruits and vegetables, one actually has to increase their food intake. Sometimes eating enough to obtain even an optimal quantity of calories from fruits and vegetables can become a significant challenge. Adding just the right amount of still healthful but more dense foods can often help fill in the gaps.

Another strategy that has become popular in the last decade for decreasing excessive calorie intake, thereby reducing the burden on the body and increasing health, is known as intermittent fasting. This usually takes the form of one of two strategies. The first is eating “normally” for 5 days per week while eating a calorie-restricted diet for two days per week. The other strategy is extending one’s daily “fast” to 16 hours per day each day; in other words, eating all of one’s food within an 8-hour time frame each day.

In the context of people eating conventionally, I love these intermittent fasting strategies. They allow the body to get a break from the calorie-dense foods commonly consumed, to allow it to “clean up” from the excess and be able to do a bit of extra maintenance and healing at the same time. It gives the body a much-needed regular break from the usual burden of overeating, which is of great benefit in so many synergistic areas.

But what about when someone is already optimizing their calorie intake by eating very large quantities of fresh fruits and vegetables, like many fruit and vegetable based raw food enthusiasts do, and then they add one of the intermittent fasting strategies on top of that? This can create a further challenge / hurdle to obtaining an adequate / optimal quantity of calories. I have had several patients and students who have found themselves with this extra challenge in their commendable attempts to be as healthy as possible.

I would rather see someone eat within a 12-hour window and fast for 12 hours per day when their diet is based on fresh fruits and vegetables, as opposed to having them try to get all of their food in within an 8-hour window so they can fast for 16 hours per day. With the latter approach, people can get pretty stressed about eating enough fruits and vegetables to obtain all of their calories within this limited time frame, especially when real life schedules factor in. They may overeat during this eating window, which means they are overburdening their digestive system, thereby putting more stress on their body. Then they will need that 16 hours of fasting per day to recover from the stress of overeating. Without the extra stress, one doesn’t need as long of a recovery period.

Another strategy I’ve seen is adding too much dense food back into one’s diet in order to obtain enough calories within the 8-hour time frame. Again, I would rather see people extend their eating time / shorten their fasting time, to be able to eat lighter, healthier foods more consistently.

Another result I’ve seen is that people can become too lean and sometimes depleted from a lack of calories (and the nutrients that come along with those calories from healthy foods), when both strategies are employed together for extended periods of time. In this case they are not optimizing their calorie intake as they are restricting too much for too long.

Having said that, I have met some who do center their diet around fresh fruits and vegetables AND engage in one of the intermittent fasting strategies, and if that is working well for them on all levels, I do not want to be the one to discourage them. But if this strategy is causing more stress and harm than good, please know it can be quite a challenge for many of us to eat enough fruits and vegetables to get to an optimal calorie intake, and if one needs some extra time to do this, then it’s not a problem in this context. One will have less stress and be less likely to feel the need to overeat or eat foods that are too dense for them to experience their optimal level of health and vitality.

In my opinion, the majority of people who over consume conventional foods could benefit from either of the intermittent fasting strategies discussed earlier that get them closer to an optimum calorie intake and allow their bodies the much-needed periodic breaks. However, when one eats healthy foods that do not cause such undue stress on the body, the periodic breaks do not need to be as long as there is less to recover from in the first place. With these shorter breaks, one usually still comes out ahead with the strategy of giving oneself longer to eat larger amounts of fruits and vegetables, all things considered.

As with all complex, multifactorial processes for which we need to make good decisions, we must consider all factors and how they interact with and affect each other. Taking one consideration out of context can sometimes lead to an out-of-balance health equation which makes it harder to achieve the results one is seeking. When this occurs, one can feel defeated because they have put a lot of effort into something that hasn’t worked as well as anticipated. This discouragement often leads to giving up and going back to conventional eating, which now means one doesn’t experience the benefits they have worked so diligently toward. We don’t want this to happen to any of you! Sometimes a key modification, such as giving oneself a few extra hours per day to consume an optimum calorie intake from a diet based on fruits and vegetables, can help one stay on the healthiest path for one's particular set of life circumstances.

We hope you have enjoyed this perspective on the intermittent fasting and fruit and vegetable centered diet combination of considerations! For more details and information on this topic, feel free to watch the 33-minute video presentation from our June 2019 webinar on this topic as seen below this article. The section on intermittent fasting begins at the 17 minute, 30 second mark, and continues until about the 51-minute mark. For those of you who like what you see and hear and would like to find out how to learn a great deal more about plant-based and raw food nutrition and how all the considerations fit together into a cohesive whole, you can keep watching to hear about our Mastering Raw Food Nutrition online curriculum. Enjoy!

The first two articles in this series on blood sugar regulation were regarding a lab measurement in the human body known as A1c and a food measurement known as the glycemic index, respectively. In this third article we discuss insulin sensitivity vs. insulin resistance. In order to get the most from this article please read the first two articles in previous blog posts below, which we will refer back to here.

Influences over Blood Sugar

There are many components of human physiology that affect our blood sugar level. This includes several interrelated hormones, the state of our autonomic nervous system, our emotions, our physical activity level, the amount of body fat and lean (muscle) tissue, amount of dietary fat consumed, type of dietary fat consumed, dietary fiber consumption, the physical structure of our cell membranes, certain nutrients, etc.

One of the key hormones involved in regulating blood sugar is known as insulin. One of the main jobs of insulin is to escort glucose, aka blood sugar, out of the blood and into the cells, where glucose can then be used to fuel cellular processes. When our cells are responsive, or sensitive to insulin, this process works properly, and glucose remains at appropriate levels in the bloodstream because it is being efficiently escorted into the cells to use for energy.

When our cells are not responsive, or resistant to insulin, the process of escorting glucose from the blood into the cells does not work as well. As a result, the glucose level in the blood remains higher than is desirable as it cannot get out of the blood and into the cells as readily. In our first article in this series on A1c we discussed some of the significant consequences of elevated blood sugar levels.

Insulin Sensitivity vs. Insulin Resistance

In our second article in this series on the glycemic index, we saw different blood sugar response curves for 4 sample people consuming straight glucose, then the same quantity of carbohydrate from bananas. We noted that the response curves varied quite a bit between individuals. How could there be such a variation in the glucose response curves when each subject was given the same quantity of food with the same glycemic index?

The answer is that some people’s cells are sensitive to insulin, while other people’s cells are resistant to insulin. Those experiencing insulin resistance have higher glucose response curves than those experiencing insulin sensitivity, no matter what they eat, even low glycemic foods! In our glucose vs. banana comparison to determine the glycemic index of bananas as described in the previous article, you may have noted that subject A had the lowest glucose curve for both glucose and banana consumption, while subject D had the highest glucose curve for both glucose and banana consumption. Subject A’s cells are sensitive to insulin, while subject D’s cells are resistant to insulin. Subjects B and C are in between on the insulin resistance vs. insulin sensitivity spectrum.

The glycemic index is a rating of the blood sugar response curve in a sample of humans RELATIVE TO THEIR GLUCOSE RESPONSE CURVE. It is not a rating of what will happen when that food is consumed by a particular individual. The state of insulin sensitivity vs. insulin resistance exerts a much greater influence. In insulin resistant individuals, every food consumed will cause a greater increase in blood sugar levels compared to someone else eating the same food who is insulin sensitive.

IF YOU HAVEN’T ALREADY, THIS WOULD BE A GREAT TIME TO REVIEW THOSE GLUCOSE RESPONSE CURVE CHARTS IN THE GLYCEMIC INDEX ARTICLE BELOW.

Insulin resistance is the hallmark of type II diabetes, pre-diabetes, and slightly elevated blood sugar. People with type II diabetes make plenty of insulin, in fact often times extra insulin, but their cells are resistant to it. That is why people with diabetes have higher glucose levels than people without diabetes, even when they eat the exact same food. This is because when insulin attempts to escort glucose out of the blood and into the cells, the cells are resistant to that process occurring as efficiently as it does under optimal conditions of insulin sensitivity.

Conventional Advice

It’s very important to note that carbohydrates are not the cause of insulin resistance. The body not being able to regulate carbohydrates well is the effect of insulin resistance.  However, the usual advice when this occurs is to limit the quantity of carbohydrates in the diet. Unfortunately, this process does very little, if anything, to correct insulin resistance, the underlying cause of the problem in the first place.

In fact, many low carbohydrate, low glycemic foods actually promote insulin resistance! Most doctors however advocate the consumption of these foods to their diabetic patients. No wonder these same doctors tell these patients that there is no cure, and that they will be on medication for the rest of their lives!

A Better Solution

In order to recover from type II diabetes, pre-diabetes, or slightly elevated blood sugar, the root causes of insulin resistance need to be addressed. When you stop causing insulin resistance, your cells become more sensitive to insulin, and blood sugar levels start to come down as a result.

In the next article in this series we will look at the major causes of insulin resistance and how to reverse the process and therefore allow elevated blood sugar levels to come back down to a more healthful range.

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Introduction

In our last newsletter we posted an article about a very useful blood sugar measurement called A1c. In this issue we look at another measurement that is often referred to when considering how to keep our blood sugar in an optimum range, known as the glycemic index. We have all heard about the glycemic index, but how is it determined, and how much relevance does it really have to the big picture of blood sugar regulation?

What is Blood Sugar?

“Blood sugar” is the concentration of a simple carbohydrate known as glucose in our blood. Glucose is the primary source of fuel for most cells in our body, so it is found in the bloodstream as it is being transported and distributed to those cells. The same characteristics that make glucose a good source of fuel also cause it to react with other molecules it comes in contact with. These “glycation” reactions lead to stiffness, inflammation, wrinkles, and a host of other problems. When this continues over time, circulation and nerve function becomes impaired, leading to numbness, tingling, amputations, vision problems, kidney problems, hypertension, heart disease, strokes, etc. It is therefore highly desirable to keep our blood sugar aka glucose levels in a healthfully low range.

The Glycemic Index

The glycemic index of a food is the degree to which that food raises blood sugar after being consumed. How though, is the glycemic index of a particular food determined? It starts by taking at least 8-10 people, feeding them a specified quantity of glucose, usually 50, 75, or 100 grams, and then measuring the blood sugar level of each participant at periodic intervals over the next two hours. In the figures below, only 4 sample subjects are shown for simplicity purposes.

Figure 1: Glucose response curves in 4 sample study subjects

As you can see, the resulting glucose response curve can vary widely depending upon the individual. Because of this, an average is taken of all of the study subjects. The “area under the curve” of the average curve is assigned a value of 100, to be used a reference point for the comparison food.

Figure 2: Average glucose response curve of study subjects

Then, under the same conditions as when given the glucose, the same study subjects consume the test food in a quantity that equals the same amount of carbohydrate as the glucose that was consumed initially. If the subjects consumed 100 grams of glucose for example, they will subsequently consume 100 grams of carbohydrate from the test food, in whole food form. Then just like with glucose, periodic blood sugar measurements are taken over the next two hours to determine the glucose response curves of the subjects for the test food, in this case bananas.

Figure 3: Bananas response curves in (the same) 4 sample study subjects

As we saw with glucose, the response curves vary among individuals. The curves are once again averaged out and an average banana response curve is obtained.

Figure 4: Average banana response curve of study subjects

Then the area under the average banana curve is compared to the area under the average glucose curve.

Figure 5: Average glucose curve vs. average banana curve

The area under the average banana curve is 52% of the area under the average glucose curve for the same individuals under the same set of circumstances. This means bananas raise blood sugar 52% as much as the same quantity of glucose consumed directly. As the average glucose response curve was assigned a glycemic index reference value of 100, bananas are assigned a glycemic index value of 52.

Figure 6: Average glucose curve vs. average banana curve determines the glycemic index of bananas.

Foods that have a glycemic index below 55 are considered low glycemic foods. From 56-69 is considered medium glycemic, while foods that rate at 70 or above are considered high glycemic foods.

Conclusion

Now is where the plot thickens. Brace yourself. As it turns out, the glycemic index is one of the least important factors in blood sugar regulation!!!  In fact, it leads to a great deal of confusion and often leads people into a false sense of confidence while they continue to sow the seeds of unhealthy blood sugar regulation.

Stay tuned for upcoming newsletter articles to continue this discussion and find out what is most important in blood sugar regulation.

Copyright 2018 Drs. Rick and Karin Dina, D.C. All Rights Reserved

One of the best ways to keep in touch with us is to join our email list. You’ll receive a free copy of Our Top 12 Strategies for Long Term Success on A Raw Plant-Based Diet eBook along with regular information about raw food and plant-based diets and periodic promotions for our classes, events, and other offerings!

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The primary measurement doctors use for testing blood sugar regulation is known as fasting glucose. Fasting in this case means the patient has not consumed any food or drink for the past 12 hours so we have a baseline, in between meals reading. Glucose, the simple carbohydrate that is the preferred source of fuel for nearly all cells in our body, is transported through the bloodstream in order to be distributed to all of those cells. A concentration of glucose between 65 and 99 mg per deciliter of blood is generally considered good and healthy, although I personally don’t like to see it rise above 90.

What if your glucose level is always within the normal range, but one time you were really stressed or scared while your blood was being drawn? Given that our glucose level tends to increase when we are stressed, your blood sugar would very likely be higher than normal. Maybe it would even be in the diabetic range, in other words 125 mg/dl or greater. Does that mean you should start medical treatment for diabetes? Probably not.  But how can you know for sure if your glucose was just high at the time your blood was drawn, or if there really is a problem overall? This is one situation where a test known as A1c comes in handy.

(Hemoglobin) A1c is a measurement of the average blood sugar level over the past few months. While being stressed at the time of a blood draw can exert a major influence over your immediate glucose level, those 10 or 20 minutes of elevated glucose will not affect the average measurement over the past few months. If A1c was measured in the same blood draw and was in the appropriately low range, that would confirm that your unusually high glucose reading was indeed unusual, and therefore nothing to worry about. Without the A1c measurement, you are still left wondering.

I have seen this type of benefit by measuring A1c in my clinical practice. I have also seen it occur the other way around, where a patient had an appropriately low glucose reading, but elevated A1c. In that case we knew there was a problem, even though the glucose measurement did not indicate it. From there we began a discussion about which dietary changes are most favorable for blood sugar to be regulated most effectively in the body. That discussion centers around insulin resistance vs. insulin sensitivity, and how the fats we do and don’t consume affect that, in addition to exercise, sleep, stress, etc. It does NOT center around avoiding carbohydrates, although making the distinction between healthy sources of carbohydrates and unhealthy ones does come into play. One of my favorite parts of going over lab results with patients is looking at the usually excellent blood sugar numbers such as glucose and A1c in high fruit eaters, but that is another story…

The bottom line for this article is that A1c can often be a very useful test when analyzed by a clinician who knows how to utilize it appropriately. Fasting glucose is very useful as well, and in certain circumstances can take the lead over A1c. In our Mastering Raw Food Nutrition curriculum, we go into a great deal of depth about the ins and outs of glucose, A1c and how it can tell the average blood sugar level, insulin, insulin resistance vs. insulin sensitivity, insulin receptor function in the cell membrane, how the fats we eat affect this and which ones to include more of in your diet and which ones to include less of, fruit, vegetables, fiber, etc. Even though it is less important than many other factors, we even discuss the glycemic index within the appropriate perspective of plant based and raw food diets and all the other variables listed above.

We hope you have enjoyed this tidbit about the usefulness of the hemoglobin A1c test!

One of the best ways to keep in touch with us is to join our email list. You’ll receive a free copy of Our Top 12 Strategies for Long Term Success on A Raw Plant-Based Diet eBook along with regular information about raw food and plant-based diets and periodic promotions for our classes, events, and other offerings!

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